Welcome to the BASICS Trial Website

The BASICS Trial is a study to determine whether antibiotic or silver impregnated VP shunts reduce early infection (within 6 months) compared to standard VP shunt in hydrocephalus following insertion of de novo shunt.

 Background & Aim

Two new devices have been introduced to try to reduce shunt infection; antibiotic-impregnated (Bactiseal) and silver-impregnated   (Silverline) shunts. This study will compare these new shunts to standard shunts in a study called a randomised multi-centre controlled trial.

This will be a national trial recruiting 1600 participants from specialist neurosurgical units. Our goal is to establish which VPS provides most protection against infection and to ensure standardisation of care and infection

rates across the country.

 

Recruitment status

Site Recruitment
Alder Hey Children's Hospital 86
The Walton Centre 119
Southampton General Hospital 146
Leeds General Infirmary 52
Queens Medical Centre-Nottingham 99
Royal Manchester Children's Hospital 37
Great Ormond Street Hospital 63
Salford Royal Hospital 57
Addenbrookes Hospital 53
Sheffield Children's Hospital 34
Royal Hallamshire Hospital 22
University Hospital of Wales-Cardiff 91
Birmingham Children's Hospital 30
Bristol 138
Kings College Hospital 32
Royal Sick Children's Hospital-Edinburgh 8
Western General Hospital- Edinburgh 5
James Cook Hospital 18
Children's University Hospital Dublin 52
The National Hospital, Queens Square 27
The Royal Victoria Infirmary, Newcastle 12
Total recruitment 1188
Table last updated 14th July 2016  

 

 
 




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